People would just blight the regions that have terrible stats. I expect Skezard on EC to be one of the first to go.
And...I'm not at all sure that would be a bad thing. Solve me a rebalancing problem real quick, that's for sure!
If the players are told, effectively, "You get to pick which 10 regions get blighted," and then they collectively do so, that may be more likely to produce results the players are willing to live with than if we just did it arbitrarily.