I found the skyscraper ad to be more than tolerable, it was actually considerably smaller than I was expecting.
Even with a 20.1 inch monitor, it sits nicely out of my way and isn't distracting enough to keep me from playing the game, though if something eye catching does pop up, I will notice it with ease.
A very slick setup, I think. Now, if only I could get another character for opting in