I think to be well rounded it is good to start with a very basic premise for each character and see how interactions would change them. Its what ends up attaching me way too much to characters and keeping it real for them at whatever cost.
Mostly I've played siblings so they have the same slightly messed up background and start out with some similar traits... now really enjoying playing a couple of the next generation... (Wulfric and Jane Fletcher). In times to come it's going to be interesting to see how Garas and Catherines kids turn out .